In order to solve the problem of power grid supply area analysis and efficiency of large-scale data sets in the dispatch and control cloud platform, a method of power grid supply area analysis based on the dispatch and control cloud model is designed in this study. Firstly, this study defines the data model of dispatch and control cloud power grid supply area. Secondly, on the basis of the data model, a method of power grid supply area analysis is designed and applied. Finally, the experiments based on the real model and topological data of the dispatch and control cloud in a regional power grid is verified. The experimental results show that the computing method of power grid supply area proposed in this study can analyze the power grid supply area in a better way, and meet the needs of the actual power grid dispatching.