Examination Arrangement is an important work task in higher education management information system. With the increasing number of students, the number of students who participate in the examination and course is also multiplied, the task of manual testing examination arrangement will become very difficult. In this paper, an algorithm using genetic algorithm is proposed. The algorithm achieves fast convergence by optimizing the mutation operation. Even for the complex examination table, it can also obtain a very high success rate and a convergence speed.