Many enterprise focus on information acquisition, state surveillance and cargo security of goods in the transportational process. The most existing monitoring system can meet the real time monitoring, but does not do the same for cargo security. In this page, the tobacco logistics distribution integration system designs based on the tobacco industry cigarette distribution business process, using GPS electronic locks, GIS e-maps of some high-tech products. Meanwhile, the designing simplifies the process of tobacco distribution, which is based on the original process and combined GPS electronic locks. And the using of tobacco logistics system showed that the system can meet the functional requirements.