Through the research and analysis of the past procurement and flow of taking materials, we put forward the concept of real-time warehouse management. During the process of taking materials, storing issue, canceling after verification for the warehouse and warehousing, with the use of wireless bar code scanning technology, the enterprise can greatly avoid the subjective causes that lead to taking and storing materials error because of the human factor; and in the procurement process, using relevance rules Apriori algorithm data mining on taking material to achieve the guidance on the procurement scheme to reduce the blindness. Thus it can realize the real-time warehouse management, improve storage efficiency and instantaneity and accuracy of inventory information.