Effective and safe data interaction across networks of different security levels is difficult due to the lack of a standard meteorological information transmission mechanism. Considering the diverse service application requirements, this study draws on the “2+1” model structure to design the architecture of the trusted interaction of meteorological service data streams across physically isolated networks. This architecture is then deployed in the demilitarized zones (DMZ) of the meteorological intranet and other networks to achieve safe data transmission and sharing across regions. After the trusted interaction architecture is outlined, application research is conducted according to specific meteorological service requirements. Finally, system function, performance, and security tests are carried out, and the transmission bottleneck and bandwidth utilization of the trusted interaction architecture are analyzed. This research can guide the practice of applying a trusted interaction architecture to improve the transmission efficiency of data streams across heterogeneous networks.