The new driver architecture VxBus was integrated in VxWorks operation system after the release of VxWorks 6.2. VxBus dirver architecture was modularized with minimal BSP support. This paper analyzes the work mode of VxBus driver architecture. We designed and implemented a type of ARINC429 interface driver based on VxBus. The implement of vxWorks driver based on VxBus has a high degree of reliability and expansibility.