With the promotion of information construction of enterprise business process, the management of core business process has become an important foundation to further improve the information level. The performance of workflow system determines how efficiently the business process flows to some extent. In this paper, quantitative relationship between performance index and database scale is sought out by quantitatively analyzing the performance of workflow system to put forward key factors and pointcuts of technology for performance optimization. On this basis, performance optimization scenarios of workflow are studied based on database mechanism in this paper and a simple effective algorithm is proposed. As a result, filing mechanism is implemented so that the ultimate goal of workflow system performance optimization can be achieved.