In order to reduce the impact fluctuation of high power fast-charging pile on the power grid, and considering the advantages of Distributed Generation (DG) and energy storage of typical fast-charging stations, an optimal operation configuration method for typical fast-charging stations of Electric Vehicles (EVs) is proposed. By analyzing the power output characteristics of the DG in the station and the charging behavior law of EVs, the optimal operation configuration model of typical fast-charging station is established taking the minimum operation cost of the charging station as the optimization objective. The optimal solution of the model is solved by genetic optimization algorithm with the constraints of the power balance in the station and the power output of the distributed power supply. Finally, the feasibility of the proposed method is verified by different configuration examples to provide technical support for the optimal operation of a typical fast-charging station.