Aiming at the increasingly heavy work of transmission line patrol and the problem of difficult patrol, high risk and low automation of Unmanned Aerial Vehicle (UAV) for transmission, a kind of intelligent patrol system and method for automatic driving of transmission line multi-rotor UAV is proposed. Combining artificial intelligence image recognition technology, the system realizes the intelligent processing of the patrol data, so that a new automatic intelligent patrol operation mode for transmission lines is established. This study focuses on the structure, function, and key technologies of the inspection system. Through the application of transmission line inspection in Foshan area, the system greatly improves the efficiency of power grid inspection, and proves its effectiveness and rationality.