The short life of battery becomes the bottleneck that greatly undermines user's experience of smart phones due to the high power loss on display panel. To overcome the challenge, a low-power and high-quality display driving algorithm based on two-line model is proposed in this study. Firstly, the original image is converted from the RGB space to the YUV space. Subsequently, the average and maximum luminance values are calculated to enable the two-line model to be established based on the corresponding average and maximal luminance values. Finally, the YUV space is converted back to the RGB space and the renewed image is obtained after generating the renewed luminance under the assistance of the two-line model. The experimental results show that the MSE of image processed by the proposed algorithm is 30.9% and 29.9% lower than that processed by the NPC and the ACSC, respectively, with the lowest power consumption. Moreover, the proposed algorithm has been successfully verified on an FPGA board without causing a significant degradation of visual effect.