In order to achieve the various parameters in the process of underground coal gasification of real-time monitoring, data analysis, and the realization of accurate control of the production process of all key variables, this study designs the underground coal gasification process measurement and control system based on PLC. This paper first introduces the underground gasification process and testing requirements analysis, secondly presents the design of overall scheme and hardware and software, finally elaborates the database and mathematical model used in the applications. The mathematical model of measurement and control system consists of three layers of topology:device layer, control layer, and monitoring layer. The equipment layer includes the basic hardware devices. The control layer includes two Siemens S7-300 series PLC station, constituting the double CPU soft redundancy system, to ensure the stable air supply in ignition lane when one PLC station fails. Monitoring layer uses the configuration KingView and Navicat Premium software. Above design realizes the real-time monitoring of data display, video image real-time monitoring, historical data storage, and so on. This project has been successful run for nearly a year in Shanjiaoshu Mine affiliated with Guizhou Panjiang Reined Coal Co. Ltd..