In order to obtain the transliteration results quickly, a multi-lingual transliteration software based on rules is designed on the basis of manual processing in this study. The software can meet the transliteration needs of various lingual, because algorithm and rule are designed separately. The complete transliteration process includes four steps of word pre-treating, letter recognition and segmentation, letter recombination and localization, and rule table searching. In the letter recombination, this study proposes a method of determining the best syllable division, which can reduce the error rate of syllable division effectively and improve the quality of final transliteration results. The results of the experiments for English, Roman, and Russian in this study show that the transliteration accuracy can reach to 95% or more.