In this study, a non-contact measurement method with interactive function is proposed by using Microsoft MixedReality product HoloLens. Measurement space can be scanned by using HoloLens depth camera, the target points can be determined for non-contact measurement purpose through gazing and gestures, calculation of the distance, area, and volume between the target points can be performed automatically, in addition to interact with the speech recognition function. Compared with traditional measurement tools, interactive measurement tools developed in this study allows non-contact measurement by using more natural interactive mode, the measured range became more widely, not only for measuring the distances, but also for calculating the areas and volumes automatically. The places which are inconvenient reached by the traditional tape measurement can be measured by non-contact measurement method proposed in this study, and which has certain application value.