The mobile Internet and health big data is causing big health healthcare management industry disruptive change, the formation of a firm focuses on building levels based on the "Internet+IoT+medical service" technology-based business model to cloud O2O health management system platform. "Zhong Ke Hui Kang" health cloud platform mainly provides health management platform for health institutions and users. This paper discusses in aspects of the platform architecture design and system optimization starting from load balancing, distributed caching, database optimization, socket forwarding server design a good cloud platform to support business development. Experimental results show that the system architecture to meet the one million level of data forwarding and user access, application practice shows the feasibility of the scheme.