Focused on the issue that software version upgrades frequently, test cycle time is compressed constantly, and the test workload gets heavy, with the combination of a enterprise application software,and based on the QTP technology platform builds a test automation framework. Firstly, this paper designs a automated testing framework for enterprise application software by understanding of the working principle of QTP and the characteristics of enterprise application software; Secondly, through the design of test case, writeing test scripts, strengthening the test script and running automated test, realizing the software automated test. Practice shows that automated testing is more suitable for regression testing because of the time-consuming of automated testing is 15% quicker than manual testing, through the useing of automated testing framework, solves the completeing a large number of test cases covering problems in a short time, guarantees the quality of released software, improves the test efficiency.