In the human-computer interaction, the keyboard far cannot satisfy the requirement of people. In this paper, a method based on gesture recognition algorithm is proposed, and combine with keyboard keys to realize intelligent input. In the algorithm, the hand region is extracted by using skin color segmentation. According to the hand shape to detect the thumb and the number of outstretched fingers, and their position, then gestures are converted into binary language computer can accept. Combined binary number with the keyboard keys, gestures are defined as the different buttons to achieve compute intelligent input. The experimental results show that the algorithm has certain robustness, and it can achieve a high success rate.