Real time monitoring of dynamic target is the essential technology and the development trend of wireless sensor network coverage. Aiming at the problem of target motion brings the dynamic network topology change and heavy energy consumption, this paper proposes a prediction algorithm. Through a comprehensive analysis of the target's information such as velocity, moving direction in the current moment, based on the two-dimensional Gauss distribution, it predicts possible future areas, which leads to activation of the corresponding sensor, alleviate the work pressure of wireless sensor network. It designs the communication protocol, to ensure the stable transmission, data between base station and sensor nodes in real time. The experiments based on simulation show the algorithm is not only valuable but also feasible.