As an important style of modern enterprise research-based company should pay more attention to improve management efficiency because of its special profit model. Management information system is an important means to enhance the management efficiency, but the development objective and the application process of the management information system will affect its result in company. A lot of management information systems become formalistic after the end of system development. It needs to be researched starting from the development goal to the development process that how to make the management information system becoming effective tools. Based on the reality of the company the management information system is developed with agile method to satisfy the daily management needs and that achieved good results.