At present, logistics distribution is the new trends of logistics, in logistics distribution, the distribution path planning is the main reason for the customer satisfaction and the total Operating costs. Using the ant colony optimization algorithm, we realize the optimization process of VRP problem for logistics distribution, the algorithm can find the best vehicle numbers and the relation path in a short time. By testing the algorithm, we find that the Convergence of the algorithm is good, when it reaches the high level of the service, the cost logistics distribution can reduce quickly.