This article draws on domain of common IT remote monitoring of the implementation of the plan. From the application point of view to design a real-time and reliable serial device remote monitoring system, causes not to have the networking function originally and to disperse the regional serial devices is connected in the ethernet, make full use of existing Internet resources for transmission and management of data. Through studies the embedded S3C2440 the module of serial port ethernet communication, designed a software program to realize, serial port ethernet communication applications in the multithreading technology, achieved serial device serial protocol and TCP/IP protocol conversion. In the program establish a remote tunnel link using OpenVPN, remote login through telnet embedded platform to monitor the embedded end. The experimental test serial data in remote monitoring and control of the computer has a good consistency and achieved the monitoring of serial devices.