For the quickly growing standards of information sharing and business integration in enterprise, SOA is often used to integrate enterprise applications because enterprise service bus can shield the heterogeneous enterprise applications. Current products of Enterprise Service Bus (ESB) are mainly based on Message Middleware technology, which do not satisty all the requirements of ESB. These products restrict the availability and scalability of ESB, and cannot meet the enterprise’s highly concurrent request and real-time response requirements. In this paper, a new architecture is first brought forward for ESB based on Plug-In technology, and then it analyzes some key technologies including capture requests, dispatch requests, real-time response etc. At last, ESB has proven to be feasible and effective by the prototype system’s application in practical projects.