A design method of the portable wireless searcher based on CC2430 is proposed. In this method, the values of RSSI of the wireless data frames from CC2430 RF card on the person in trouble sent to the searcher are changed into the distance values between the person in trouble and the searcher by mathematic transform, thus the above distance and the location of the person are estimated. Furthermore, this method uses schedule algorithm to optimize the communication and improve the stability of the data transmission in busy com- munication. The experiments show that the design method provides good accuracy and sensitivity, and can meet the requirement in reality.