Visual simulation of material supply for large ships could visually simulate the handling process, calculate the handling time, find the bottleneck and further optimize the handling process. Firstly, the supply type and handling process of large ships are qualitatively analyzed. After that, the visual simulation system structure based on Flexsim of material supply on large ships is proposed. The simulation model is designed and the key technologies used in the simulation platform are discussed. With a specific example, several simulation experiments are done through the simulation platform. The results show that visual simulation is very useful for the design and operation management of material supply handling system in a large ship.