For the lack of existing RFID systems, to design an Active RFID systems based on ZigBee technology. This paper elaborates hardware design of active RFID systems, respectively gives software architecture of reader and active tag, and completes the communication between reader and active tag by studying the Z-Stack protocol. TI’s CC2591 power amplifier chip is adopted, increasing the communication range of reader and tag. And low-power design is achieved by increasing in sleep time and reducing communication flows. Ultimately the long-range, multi-node active RFID system is realized in this paper.