This paper describes the importance of safety information in safe management of mines and compares traditional safety information management modes with modern ones. For all disadvantages of the traditional management modes, it designes a non-coal mines MIS based on authentication and electronic signature. The function of system, system platform, the DC role, the distribution of competences are designed. It also elaborates the design of system module-function in detail. The comprehensive use of authentication and electronic signature technology based on USB-Key effectively guarantees information’s integrity, reliability and security and prevents identity theft and operation denying. It has improved the efficiency of supervision and monitor accuracy, increased the strength and breadth of supervision, standardized business processes. The non-coal mines MIS is simple, efficient, safe and scientific.