Amid the continuous innovation in medical technology, medical staff’s demand for relevant information systems is increasing. As required by the clinical practices of doctors and nurses, an information management system suitable for the catheterization laboratory is developed and connected to the original systems of HIS and PACS in the hospital. This system builds on the Client/Server (C/S) model, which is equipped with the C# programming language and the SQL server database. In light of clinical needs, it serves the information management system for the Digital Subtraction Angiography (DSA) catheterization laboratory, with the functions including registration before operation; interventional therapy, medication and consumables recording, nursing evaluation, coronary angiography, and image acquisition during operation; report template setting, operation logging, operation recording and complex query after operation.