In order to satisfy the demands of meteorological applications in prefecture-level city, aiming at the existing problems such as low reliability, poor scalability, and low concurrent processing ability of information system, this study adopts virtualization technology, load balancing strategy configuration, and linkage technology with virtualization. It designs and builds a virtualized resource platform to realize the expansion and recovery of dynamic resources. At the same time, this study designs and implements an application-based load balancing method and applies it to the actual meteorological domain. At present, the system has been put into operation. It provides stable and efficient application support for city and county meteorological applications. It obtains better application results.